Antibody Physicochemical Properties Analysis Service

$6200

CD ComputaBio understands that each project is unique, and our team tailors the approach to address the specific requirements of our clients, ensuring that the delivered solutions are precisely aligned with their objectives and expectations.

Inquiry

Overview

Antibodies are large biological proteins with many physicochemical properties such as molecular weight, isoelectric point, and solubility.CD ComputaBio specializes in providing cutting-edge antibody physicochemical property analysis services to meet the complex needs of the biotechnology and pharmaceutical industries. Our focus on precision, accuracy and innovation enables us to provide comprehensive insights that enable researchers and organizations to advance antibody development with confidence.

Our Services

Figure 1. Antibody Physicochemical Properties Analysis Service

Molecular Weight Calculation: based on the amino acid sequence of an antibody, the theoretical molecular weight of an antibody can be calculated.
Local Charge Distribution: Determining the charge distribution of an antibody molecule can help to understand the solubility and stability of the molecule, as well as its interactions with other molecules.
Calculation of Hydrophobicity and Hydrophilicity: By calculating the hydrophobicity and hydrophilicity of an antibody molecule, the behavior and stability of the antibody molecule in solution can be predicted.
Interstructure Prediction: Based on the amino acid sequence of an antibody, it is possible to predict its three-dimensional structure, including the secondary (e.g., alpha helix, beta folding) and tertiary structure of the protein.
Structural Stability: The structural stability of an antibody can be assessed by calculating the interaction forces between amino acid residues in different parts of the antibody (e.g., hydrogen bonding, hydrophobic interactions, etc.) or by molecular dynamics simulations, among other methods.

Our Methods

At CD ComputaBio, we leverage a suite of proprietary algorithms developed and refined by our experienced team of computational biologists.

Antibody Optimization

Our expertise also includes antibody optimization, where our algorithms help refine candidate lead antibodies to enhance their affinity, specificity and stability. Through iterative computational simulation and predictive modeling, antibody sequences are fine-tuned to generate superior variants with enhanced therapeutic properties.

Data Analysis and Interpretation

We offer advanced data analysis and interpretation services. Our computational tools provide in-depth analysis of screening results, helping to identify patterns, trends, and key parameters that affect antibody performance. We enable our clients to make informed decisions and streamline their antibody development process.

Molecular Dynamics Simulation

Molecular dynamics simulation is to analyze the dynamic behavior of molecular systems by simulating the Newtonian mechanics of atomic motion, and the results can be used to analyze the three-dimensional structure of biological macromolecules such as proteins and antibodies, as well as their dynamics, in order to understand their physicochemical properties and mechanisms of action.

Service Highlight

Comprehensive Reports

We provide comprehensive reports detailing the results of each analysis, along with clear explanations and actionable insights.
Fast turnaround

Our streamlined processes and efficient workflows enable us to deliver timely results.
Collaborative Partnerships

We value our partnerships with clients and actively work with research teams to ensure our analyses are aligned with their objectives.

CD ComputaBio is a trusted partner for organizations seeking insight into the physicochemical properties of antibodies. With our team of seasoned experts and our dedication to staying at the forefront of technological and algorithmic advancements, CD ComputaBio offers unmatched expertise in antibody physicochemical properties analysis. Our dedication to excellence, innovation, and collaboration allows us to provide analytical services that enable our clients to make informed decisions and advance antibody development with confidence.